Abstract:

The aim was to study the powder-characteristics of drug-diet maca, 3 natural plant auxiliary materials and the processing parameters of direct compression technology of the compound maca-powder. By single factor and orthodox experiment, the powder-characteristics such as bulk density, tap density, angle of repose, swelling ability were investigated, SAS software was applied in the calculation. The results showed that the powder of natural plant A, B and maca all had good fillibility. The flowability had important influence on the fractionated dose of the compound maca-powder. The powder A, B used as auxiliary materials had significant effect on the bulk density (P=0.0125), volume swelling (P=0.0089) and little effect on the tap density of the compound maca-powder. The optimum condition of compound maca-powder swelling volume was obtained as follows: A was about 0.15 shares B was about 0.10 shares, C was about 0.05 shares, and the optimum swelling volume was about 2.459. The technology was reasonable in formulation and satisfactory in fillibility, swelling ability, flowability, and it could serve as theoretical basis for the industrial production of maca tablets.