Abstract: In order to study the resistance of cashew to powdery mildew disease in Mozambique, and find the cashew clones that are resistant to powdery mildew disease. In Nampula Province of Mozambique, the damage of cashew fruit of 60 cashew clones caused by powdery mildew disease was investigated. The result indicated that, under the same condition, the cashew nut damage degree of different cashew clones were different. The damage degree of AC34 and 4.2VM were the lowest. The next were AZA17/79, B4, H1 and M96-2.3VM. The damage rates and damage indexes of other clones were higher relatively. According to the resistance evaluation criteria of cashew to powdery mildew disease in this paper, there were 6 high resistant clones, 1 resistant clone, 9 medium resistant clones, 21 susceptible clones and 23 high susceptible clones in the 60 investigated cashew clones. The susceptible and high susceptible clones account for 73.3% of the total samples. The most cashew clones in Mozambique were low resistant to powdery mildew disease.