Abstract: Objective：The extraction technology of caffeotannic acid from Lonicera confuse DC. leaf was studied with water as solvent.Methods：Main factors influencing the extraction of caffeotannic acid from the leaves of Lonicera confuse DC. were studied by single factor experiments,and then optimized conditions for the extraction of caffeotannic acid were studied by orthogonal test.Results：Optimized conditions were obtained as follows:extraction temperature 100℃；pH=4；extraction time 1h；material to solvent 1:18.Conclusion：The extraction ratio of caffeotannic acid was 2.83% in the optimized conditions.