Abstract: The main types of aroma substances in flue-cured tobacco leaves and the factors influencing its content were reviewed in this paper. It was thought that genetic and ecological environment variance, cultivation and curing practices were the main limiting factors for improving aroma substance content. Moreover, it was suggest that transplanting at reasonable time and density, optimal fertilization, harvest and curing when leaves mature, as well as chemical control technology, have more potential to improve aroma substance content in flue-curd tobacco leaves.