Abstract: This article explored the Corporate Social Responsibility of the food supply chain management in terms of core business enterprise. It outlined the content of Corporate Social Responsibility in food industry from the layer model and the characteristics of Corporate Social Responsibility in the food supply chain, analyzed the key role of core business enterprise in food supply chain management. It is the key to improve the management of Corporate Social Responsibility in the whole chain that the core business enterprise and the other members of the chain to implement social responsibility together. It set up the constraint and delivering mechanism from the point of the corporate culture and the information sharing, and illustrated the role and conducts of core business enterprise. To promote the sustainable development of food supply chain, the core business enterprise should develop suppliers’ active consciousness of social responsibility actively, ease their cost pressure and enhance the supervise to suppliers’ social responsibility implement etc.