Abstract: This study investigated the effects of mechanization cultivation in different planting patterns on the physical and chemical character of soil and the root tubers yield of cassava. The cassava cultivar SC205 was used as material, and the planting patterns of wide-narrow row, equidistant row and small row spacing-large plant spacing were compared in this study. The physical and chemical character of soil and the root tubers yield of cassava were analyzed during the experiment. The results showed that, compared with the planting patterns of the equidistant row and small row spacing-large plant spacing, the planting patterns of wide-narrow row not only could decrease the soil unit weight, increase the holes percent of soil, promote microbe activity in the soil, increase the contents of soil available N, P, K, but also promote the germination percentage, promote the stems and leaves of cassava growth, increase the yield of cassava. Besides, compared with the planting patterns of the equidistant row which had the same plant density with wide-narrow row, the planting patterns of wide-narrow row those the soil unit weight decreased by 2.56%, the holes percent of soil increased by 2.87%, and the yield of cassava increased by 8.07%. This showed that the planting patterns of wide-narrow row was adapted to the mechanization cultivation in cassava, it was valued in further experiment, demonstration and promotion.