Abstract: In order to explore the impact of different drip irrigation periods on the cotton fields of seedling water, salt distribution and growing of cotton. Selecting 121 Mission where continuous applying drip irrigation 0-16 years, 8 similar plots of the cotton field to monitor the water and salt chances, to test and analyze of water-salt transport at seedling stage in every cotton fields. The results initially showed that: the land which has been used of drip irrigation more than seven years, salt cotton had upward trend from the surface to the deep. The land which has been used of drip irrigation less than seven years and the wasteland, salt content had decreased gradually from surface to deep. After the first irrigation, water and salt which soil move away from the drip in the horizontal direction. Salt gradually gathered in the film gap 0-10 cm depth by evaporation. In the vertical direction, water carried salt which from the soil movement down to 90 cm below, 0-20 cm soil depth reservoir salt changes was negative. Cotton which had used drip irrigation within seven years, seedling emergence and average height increased with the increase in the number of years of drip application. Drip irrigation for more than seven years cotton germination rate basically stable at more than 83%. The application of drip irrigation more than seven years cotton seedling plant height get basic stability.