Abstract: Using 2000 to 2011 employment by industry in Xinjiang, demographic data, administrative area and administrative zoning map and other information, the use of geostatistics, time series analysis methods, combined with GIS, Geoda spatial analysis tools within the secondary industry in Xinjiang the spatial structure and timing variations were analyzed, the study found: (1)2011 Xinjiang second intra- industry mining, manufacturing, electricity, heat, gas and water production and supply industry, construction, respectively, showing the two independent center - periphery structure, the two‘C’- type structure,‘one axis wings’structure, and the‘Yi’type structure; (2)2011 Xinjiang regions within each industry, there is a second space industry agglomeration; Aksu, Kashi is the mining, manufacturing remarkable gathering area; Aksu Area is remarkable power industry gathering area. (3)2000 to 2011 secondary industry in Xinjiang during the internal structure of the industry changes in the larger proportion of which mining and power industry for changes in the internal structure of the secondary industry plays an important role.