Progress in Mass Spectrometry and its Application in Proteomics

doi:10.11924/j.issn.1000-6850.2014-0018

Abstract

Abstract: With the rapid development of proteomics, biological mass spectrometry technology had provided the profound application in proteomics, it was gradually becoming the core technology in this field. In order to reveal the specific application of biological mass spectrometry technology systemly in proteomics. In this paper, we reviewed the development of biological mass spectrometers and the applications of biological mass spectrometry technology in protein identification, posttranslational modifications and quantitation of proteins. Biological mass spectrometry technology promoted the process of the proteomics, but the complexity of the sample and the tremendous of data analysis was inevitable challenge for the technology. We believe that with the consummation and evolution of biological mass spectrometry technology, it would play a greater role in the proteomics.

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