Abstract: In order to get the control effect of rice stripe blight, the control effect of 20% iodine oligosaccharide acids against rice stripe blight was tested in field by 8% Ningnanmycin AS 1000 times diluent as the control medicament. The results of the field control effect showed that 20% iodine oligosaccharide acids 1000 times diluent＞20% iodine oligosaccharide acids 1500 times diluent＞8% Ningnanmycin AS 1000 times diluent＞20% iodine oligosaccharide acids 2000 times diluent＞20% iodine oligosaccharide acids 3000 times diluent, and the control effect was 67.47%、64.26%、62.25%、59.04% and 52.01% , respectively. The significant analysis of control effect of rice stripe blight showed the control effect of 20% iodine oligosaccharide acids 1000 times diluent and 1500 times diluent had significant difference to 3000 times diluent, and four kinds of 20% iodine oligosaccharide acids diluents were equal to 8% Ningnanmycin AS diluted 1000 times diluent at P=0.05 level. Compared with spraying water, the rice of experimental area by spraying 20% iodine oligosaccharide acids grew better. 20% iodine oligosaccharide acids had a certain control effect on rice stripe blight and promoting the growth of rice. But rice stripe blight was an important virus disease of rice, there was no effective agentia so far, we needed to take comprehensive prevention and control measures to reduce the harm caused by the disease.