Abstract: The authors comprehensively evaluated 17 fungicides varieties by comparing the efficacy and the cost on banana leaf spot disease. The results showed that 25% difenoconazole EC had better efficiency and lower cost than other fungicides. It could be commonly used as conventional fungicides in the production. The effect of 37% difenoconazole water dispersible granule was optimal, and the cost was medium, which also could be used as conventional fungicides. 40% propiconazole EW can be used for emergency situation which had better efficacy but high cost. 25% tebuconazole aqueous emulsion and 50% propiconazole EC had poor control efficiency and moderate cost, they were not recommended to cure the banana leaf spot disease from economic respect, but they could be used as rotation fungicides in delaying disease resistance. The efficacy of 300 g/L benzoic·propiconazole EC, 25% EC propiconazole, 32% myclobutanil·MZ WP and 70% water dispersible granule epoxiconazole pharmaceutical agents for banana leaf spot were similar. The price of these fungicides from low to high was: 70% epoxiconazole WDG, 32% myclobutanil·MZ WP, 25% propiconazole EC, 300 g/L benzoic·propiconazole EC. Among 20% difenoconazole yl microemulsions, 12.5% epoxiconazole suspensions, 25% tebuconazole EC, 250 g/L EC propiconazole, 250 g/L difenoconazole EC and 6% micro tebuconazole, for controlling the banana leaf spot disease, the proper selecting order was: 250 g/L difenoconazole EC, 25% tebuconazole yl EC, 20% difenoconazole azole microemulsion and 6% tebuconazole microemulsions, 250 g/L propiconazole EC, and 12.5% epoxiconazole suspension. According to the above efficacy measurement and the comparison of control efficiency and price of treatments, we provided farmers with reasonable proposals for scientific treatment of black leaf spot disease.