Abstract: Karst rocky desertification is an entity of evolution and landscape that mainly occurred against the background of the tropical, subtropical belt and warm temperature zone vegetation is destroyed, its main phenomena can be summarized as follows: eroded seriously, bedrock and gravels are exposed, the land productivity declines seriously, and at last the karst succeeds to desert liked landscapes under human activities and natural forces on the vulnerable environment of ecology and geology. Through analysis of the dynamic evolution and geosciences of karst rocky desertification, this paper took the east of Guizhou province as a study area in multi- temporal Landsat images of 1999 and 2006 to explore a monitoring method using change detection based on dynamic characteristics. This study concluded that methods based on multi- temporal remote sensing contributed to a more scientific study of rocky desertification evolution and the relief of the disaster.