Abstract: The author took sheep manure as raw material, added three different microbial agents and used high temperature aerobic composting to study temperature, moisture content, pH, germination seed index and other factors during the composting pile of sheep manure. The results showed that adding microbial agents into composting had better effect than the control (without adding any agents), the best microbial agent was provided by Gansu Provincial Academy of Agricultural Science and Technology .The temperatures of composting rose fast, entering high-temperature phase after 1 d and the high temperature period lasted for 34 d. At the end of the composting, composting pH was 7.56, seed germination index was 94.32%, EC value was the minimum and nitrogen content increased largely, reached the safety standards of composting.