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Chinese Agricultural Science Bulletin ›› 2015, Vol. 31 ›› Issue (2): 75-79.doi: 10.11924/j.issn.1000-6850.2014-1879

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Anti-inflammatory and Analgesic Activities of Danqiao Perfusate

Wei Liqin1,2, Wang Dongsheng2, Miao Xiaolou2, Zhang Shidong2, Dong Shuwei2, Kuang Xiaojiao2, Yang Zhiqiang2, Yu Sijiu1, Yan Zuoting2   

  1. (1College of Veterinary Medicine,Gansu Agricultural University, Lanzhou 730070;2Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS/Engineering & Technology Research Center of Traditional Chinese Veterinary Medicine of Gansu Province, Lanzhou 730050)
  • Received:2014-07-07 Revised:2015-01-10 Accepted:2014-09-09 Online:2015-03-19 Published:2015-03-19

Abstract: To study the anti-inflammatory and analgesic activities of Danqiao perfusate, xylene-induced ear swelling and cotton pellet-induced granuloma tissue formation tests in mice were conducted to evaluate the anti-inflammatory activity , acetic acid-induced writhing response, and formalin tests in mice were conducted to assess the analgesic activity. The results showed that Danqiao perfusate ( 40 g/kg、20 g/kg、10 g/kg) could inhibit xylene-induced ear swelling, suppress granulomatous tissue formation, decrease aceticacid-induced writhing numbers and formalin-induced licking foot times in mice. All of these results suggested that Danqiao perfusate has possess the significant anti-inflammatory and analgesic activities.