Abstract: A mango cultivar ‘Guifei’ (Mangifera indica L.) was used to study the effect of naphthaleneacetic acid (NAA) and Atonik on the yield and fruit quality. The results showed that Atonik treatment had a better effect on the yield, the yield of treatment with 100 mg/L Atonik was the highest and increased 102.6% than the contrast, lower concentration of NAA could significantly increase yield, higher concentrations had the effect of thinning and could not significantly increase yield. NAA could promote fruit enlargement obvious, but Atonik could not. NAA treatment and lower concentrations of Atonik treatment (5 and 10 mg/L) delayed the degradation of mango peel’s chlorophyll, NAA and Atonik treatments promoted accumulation of carotenoid, higher concentrations of NAA treatment (60 and 100 mg/L) inhibited synthesis of anthocyanin, NAA 100 mg/L caused adverse effects on the fruit harvest and ripening period coloring. NAA and Atonik had a little effect on the internal quality of the fruit. According to comprehensive comparison, treatments with NAA 30 mg/L and Atonik 100 mg/L were suitable. This study will provide reference for the security production of mango fruit.