Abstract: To solve the problem of rare rooting of the cuttings of Tamarix taklamakanensis, the pioneer trees for sand fixation on mobile sand, the authors conducted tests to screen the key factors, such as the cutting medium, cutting length, cutting lignification degree and exogenous external treatment, and discussed the optimization conditions for cutting propagation. The results showed that the cutting propagation ability of Tamarix taklamakanensis is generally low, with the survival rate of cuttings between 6.67% to 31.11%. The optimum cutting was the hard branch one with the length of 15 cm, the survival rate of cuttage reched 31.11% in hard-wood cutting and 10.37% in cutting with the length of 15 cm. The optimum medium was the loam with moisturizing performance, cutting survival rate was 9.63% . The effect of external hormones treatment on rooting was significant, especially those treated with 200 mg/L IBA for 20 min, in which, the rooting ratio reached 14.07% and was 6 to 7 times of CK treatments. Among treantments with different concentrations, the survival rate of cuttings treated with 200 mg/L IBA was 22.22% , while among treatments with different durations, the survival rate of cuttings treated with IBA for 20 min was 24.44%.