Research Progress of Jinggangmycin

doi:10.11924/j.issn.1000-6850.casb15020060

Abstract

Abstract: Jinggangmycin is one of the most successful bio-pesticides and is mainly used to protect Oryza sativa against Rhizoctonia solani. This paper reviewed the physicochemical property of jinggangmycin and the researches about the bioactivity of Jinggangmycin. jinggangmycin not only inhibited the activity of trehalase, cellulose-degrading enzymes and polygalacturonase but also affected the biosynthesis of inositol. Then the author summed up the detection method of Jinggangmycin. The lowest limit of jinggangmycin that could be detected was 0.4 ng with the LC-MS or GC-MS method. Then biosynthesis pathway of jinggangmycin was put forward, which was producing sedoheptulose-7-phosphate using glucose by pentose phosphate pathway and then catalyzing glucose and sedoheptulose-7-phosphate by 10 enzymes. The manufacturing technique of jinggangmycin has been greatly improved with the optimization of media components and feed-batch, the control of fermentation conditions and the separation process.

Xu Lijian,Zhao Wei,Cao Cong,Wang Jian,Wang Qian and Wang Qinggui. Research Progress of Jinggangmycin[J]. Chinese Agricultural Science Bulletin, 2015, 31(22): 191-198.

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