Welcome to Chinese Agricultural Science Bulletin,

Chinese Agricultural Science Bulletin ›› 2015, Vol. 31 ›› Issue (30): 210-214.doi: 10.11924/j.issn.1000-6850.casb15040070

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Research Progress of Dicer-like in Plants

Li Rui, Wang Tian, Wen Liwei, Zhu Hongliang   

  1. (College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083)
  • Received:2015-04-08 Revised:2015-10-08 Accepted:2015-06-23 Online:2015-10-29 Published:2015-10-29

Abstract: Dicer was an endonuclease, which was a member of the RNaseⅢ family. Its homologous protein was called Dicer-like (DCL) in plants. Generally, Dicer was composed of six domains, DEAD box, helicase-C, DUF283, PAZ, RNase III, and dsRBD. The six domains contacted closely to each other and worked together. In order to improve the understanding of the functions of DCL in plants, this article summarized the protein domains of DCL, their crucial roles in small RNA synthesis and the biochemical function in several model plants, demonstrated that different types of DCL proteins showed relatively independent and closely linked relationships in small RNA production. DCL could discern the kind of RNA substrates and the exact cut sites, and would be the focus of biochemical function study of Dicers.