Abstract: This article explored the best sowing date and the optimum fertilization level of new wheat variety ‘Wen Mai No.10’ to provide foundation for its timely sowing, rational planting and scientific fertilization. With orthogonal experiment method of two factors and three levels, the new wheat variety ‘Wen Mai No.10’ was used as material, the effects of different sowing dates, different fertilization levels, and interaction of sowing date and fertilization level on yield of ‘Wen Mai No.10’ were compared. The results showed that: in all combination treatments, the yield of A₁B₃ treatment was slightly higher than that of other treatments, its average yield was 4.06 kg/10m², ranked No.1. By doing variance analysis, the yield difference of different treatments and inter blocks were highly significant, but the difference of interaction of sowing date and fertilization was not significant. The results also showed that the best sowing date of ‘Wen Mai No.10’ was early November, and the optimum fertilization level was 375 g/10m². In terms of whole growth period, three different sowing dates had no significant effect on the whole growth period of ‘Wen Mai No.10’.