Abstract: In order to analyze the soil nutrient change of Henan Province and provide reference for fertilizer application, spatial-temporal variation of mass fraction of soil effective zinc of 2 periods (1982 and 2009) were studied with the methods of GIS and geostatistics. The results showed that: the percentage of effective zinc in Henan Province increased by 41.67% from 1982 to 2009, the variable coefficient of effective zinc was 29.1% and 37.3%, respectively, in the two periods, which belonged to medium class; the optimal fitting model was spherical model, which had medium spatial correlation. For more than 20 years, the content of the effective zinc showed a decrease trend only in the north of Henan Province, and it showed an increase trend in different degrees in other regions, the growing rates of Luohe, Zhumadian and Xinyang were great, and the decreasing rates of Jiaozuo and Kaifeng were obvious. In the process of fertilizer application and soil management, the reasonable range of effective zinc should be controlled.