Abstract: In order to explore the application of organic binder in commercial organic fertilizer granulation and to provide a reference for the large-scale production of organic fertilizer, taken the composts of stems and leaves of banana and pineapple as raw materials, the granulation experiments were carried out by using three kinds of organic binders. Results showed that the three kinds of organic binders in appropriate concentrations could be used to make the organic fertilizer powders of stems and leaves of banana and pineapple to be granulated. With the concentrations of concentrated yeast wastewater, corn starch and polyvinyl alcohol as 70%, 6% and 2% respectively, the granulation effects were the best, the granulation rate was greater than 97%, and the return rate was lower than 7.93%. According to the analysis of the particle properties, 2% PVA was the most suitable for the granulation in the three kinds of organic binders, its particle size distribution was uniform, the compressive strength was 7.4 N, the water absorption rate was 2.97, and the equilibrium water content was 76.98%. The particle produced by 6% corn starch and 2% polyvinyl alcohol binder had lower disintegration rate, which could be used for further development of the slow release fertilizer.