Abstract: In order to study the climate change characteristics of Guanzhong-Tianshui economic region, based on the daily air temperature and precipitation observation data of this region from seven cities and one district during 1960 to 2014, the climate change characteristics were analyzed by the method of climate tendency rate, accumulative anomalies, Morlet wavelet function, Mann-Kendall nonparametric test method, moving t-test and Yamamoto analysis. The results showed that the annual average temperature, annual mean maximum and minimum temperature, precipitation intensity increased in recent 55 years in Guanzhong-Tianshui economic region, the annual precipitation and precipitation days reduced. The 1990s was the turning point of climate change, the increasing rates of precipitation and the annual mean temperature were significantly higher than that of other times. The precipitation amount showed a periodic change trend of 6, 14, 22 and 32 years, the precipitation intensity showed a periodic change trend of 6, 10, 22, 27 and 32 years, and the annual mean temperature showed a periodic change trend of 28 and 22 years. The mutation of precipitation was weak and that of temperature was relatively strong. The warmer and wetter climatic changing was the major trend in Guanzhong-Tianshui economic region.