Abstract: This paper analyzed the variation characteristics and the impact factors of evaporation in Quzhou, based on the monthly meteorological elements at 5 meteorological stations during 1973 to 2013, and various methods were used for analysis, including linear trend trendency estimation, correlation analysis, Mann-Kendall nonparametric test, and multiple regression analysis. The results showed that: the annual and seasonal evaporation were shown significant ascending trend in the east and middle Quzhou, especially in the recent decade; the annual, summer and winter evaporation were shown significant declining trend in the west Quzhou; the declining rate for annual evaporation in west region was smaller than the ascending rate in east and middle region; the seasonal evaporation was the highest in summer and lowest in winter; the monthly evaporation was shown a single peak variation, and peak value was in July; the mutation for the annual and seasonal evaporation occurred in the east and middle Quzhou, while the mutation for the annual, spring, summer and winter evaporation occurred in the west region; the annual amount of evaporation had a negative relationship with the relative humidity, vapour pressure and the precipitation, while it had a positive relationship with the mean maximum air temperature, diurnal air temperature range. The main factor accounted for the ascending of the evaporation in the east and middle Quzhou, was the reduction of relative humidity and the vapour pressure, the ascent of the mean air temperature and the increase of diurnal air temperature range.