Abstract: To screen the fertilizers suitable for Jiangsu wheat growth and increase fertilizer utilization rate, we used Xinlianxin controlled release urea, zinc urea and manganese urea to study their effects on wheat yield. The results showed that Xinlianxin controlled release urea and Mn urea were appropriate for wheat production in Jiangsu, the wheat yield increased by 7.32% and 4.27% compared with common urea, nitrogen utilizationrate reached 32.85% and 23.75%, respectively. However, the effects of Xinlianxin zinc urea and common urea with zinc treatment on wheat yield were poor. It was not suitable to apply zinc fertilizer to the soil with high zinc content. The results provide a theoretical basis for wheat production and promotion.