Abstract: The pot experiment was designed to explore the effects on soil pH and the cadmium contents in tobacco when different levels of quicklime fertilizer was added at different tobacco growing stage under Cd stress. The different levels of quicklime including CK、T1、T2、T3(0kg/ha、1125kg/ha、2250kg/ha、3375kg/ha),the four levels of quicklime were added into soil at resettling, fast growing and maturing stages. After the harvest, the plant samples were gathered to analyze related indexes. The results showed that soil pH was significantly improved after quicklime was added into soil , and the order of soil pH was T3>T2>T1>CK. Meanwhile, the total Cd contents in different tobacco organs was significantly decreased when the T2 treatment was applied at resettling stage; after the quicklime was applied at fast growing stage, the total Cd content in different tobacco organs was declined in different degrees , the total Cd contents in tobacco leaves was decreased with a maximum reduction that was 60.2%below the control, which was significantly lower than other treatments; the total Cd contents was decreased in tobacco root, stem and leaves after the quicklime was applied, but it hasn’t significantly affection in tobacco seed. Besides, the correlation analysis showed that soil pH and the total Cd contents in tobacco root were significantly negatively correlated with the total Cd in tobacco seed. Thus it can be seen T2 treatment with 2250kg quicklime per hectare can significantly improve the soil pH ,decrease Cd absorption in root and efficiently reduce Cd content in tobacco leaves in the whole growth stage. So the application of T2 treatment was suitable for the Cd polluted soil.