Abstract: To achieve scientific fertilization for peanut. Field experiments were conducted to study the influence of combined application of N, P and K on peanut yield, nutrient absorption, accumulation of dry matter, and the fertilizer utilization ratio. The results showed that treatment with NPK fertilization and farmers fertilizer, the yield increased by 46.82% and 7.53% respectively; the yield increased rate of N,P and K fertilizers application was 27.80%, 13.56% and 21.12%, respectively. With nutrient accumulation more farmers NPK fertilization increased by 13.30%, 36.48% and 40.75%, respectively, the material utilization ratio of N, P and K fertilizers were 33.39%, 15.17% and 39.02%, respectively. The combined application of N, P and K (N-90, P2O5-120, K2O-150 kg/hm2) promoted the peanuts for N, P and K nutrient absorption and utilization, and increased the yield of peanut, therefore, it can be used as formula fertilizer of achieving high yield of fluvo-aquic soil in peanut.