Abstract: Based on the lightning monitoring and positioning data and the statistical data of lightning disaster of Yunnan Province in 2008—2017, the temporal and spatial distribution of lightning activity was analyzed, and a comprehensive evaluation index system of lightning vulnerability was established, which included lightning risk, regional risk and risk of disaster bearing body. The index weight judgment matrix was constructed by the analytic hierarchy process (AHP). Comprehensive evaluation index R conversion equation was obtained to determine the vulnerability degree of lightning disaster in each prefecture, and form lightning risk vulnerability zoning in Yunnan Province. The results show that Kunming and Yuxi are the high vulnerability areas of lightning disaster, where population density and economic development are high, the comprehensive evaluation index of the lightning damage vulnerability is high and lightning affects a wide range of areas and industry; the second high vulnerability areas are Pu’er, Qujing, Lijiang, Chuxiong, Honghe and Xishuangbanna, and the areas of this grade are most widely distributed; the medium vulnerability areas are Baoshan, Zhaotong, Lincang, Wenshan and Dali. Diqing, Nujiang and Dehong are low vulnerable areas of lightning disaster. Strengthening the construction of lightning protection facilities, expanding the early warning coverage and enhancing the popularization of lightning protection can improve the resilience to disaster