The Advance of Exosomes Regulating Oocyte Development in Ovarian Follicle

doi:10.11924/j.issn.1000-6850.casb18040029

Abstract

Abstract: In order to explore the regulation and mechanism of Exosomes(EXs)-mediated regulation of oocyte growth and subsequent fertilization in the follicles, recent literatures on EXs have been summarized. Firstly, the composition and function of EXs were reviewed. Secondly, on this basis, we focused on how EXs regulates the interaction mechanism of oocytes and follicle somatic cells in follicles. Finally, we further analyzed EXs mediated sperm fertilization regulation mechanism. Thus, the conclusion is proposed, which EXs regulate the oocyte growth and development through the protein and RNA contained in the follicles in the follicles. It is suggested that the research on the regulation of oocyte growth and development should pay attention to the study of EXs. In the end, the effects of EXs on the development of oocytes were systematically discussed for the first time, and it is expected that they have a certain significance for the research counterparts.

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