Abstract: To screen fine wheat varieties suitable for cultivation in dry farming area of Shandong Province, under the condition of rain cultivation in field,‘Jimai 5265’,‘Lumai 13’,‘Jimai 22’,‘Linmai 6’,‘Qingmai 6’were used as materials. The SPAD value, net photosynthetic rate, transpiration rate and other related indexes of wheat flag leaf as well as yield were detected by the chlorophyll meter and photosynthetic apparatus. The results showed that drought stress reduced the SPAD value of flag leaf of wheat. The SPAD value of‘Jimai 22’and ‘Linmai 6’was relatively high, which indicated that the chlorophyll content was high, and flag leaf had strong ability to produce photosynthate and strong drought resistance. Drought stress reduced the photosynthetic rate of flag leaf of wheat; the photosynthetic rate of‘Jimai 22’decreased more, while that of‘Qingmai 6’reduced less.‘Qingmai 6’had more drought resistance than‘Jimai 22’. Under drought stress,‘Lumai 13’and ‘Qingmai 6’could maintain high photosynthetic rate under high transpiration rate. Taken together, under the condition of adequate water,‘Jimai 5265’and‘Jimai 22’are suitable for popularizing in this area, under drought condition, the yield of‘Lumai 13’and‘Qingmai 6’is relatively stable.