Abstract: An investigation of nutrients management on mulberry was carried out including 44 mulberry orchards distributed in main product area in Hubei province. It was showed that 75.0 and 100 percent mulberry orchards was applied organic manure and inorganic fertilizer. The average N, P2O5 and K2O application rates were 453.0kg/hm2, 114.0kg/hm2 and 175.5kg/hm2, respectively, which ratio was 1:0.25:0.39. Organic resource N, P and K account for 25.5%, 69.7% and 87.2%. The result illuminated that N, P and K applied rates in east Hubei were larger than that of in other main area. The results showed that N application rate over 600 kg/hm2 orchards was 15.9 percent while below 150 kg/hm2 was 22.7 percent, P2O5 application rate over 225 kg/hm2 orchards was 6.8 percent while below 75 kg/hm2 was 22.7 percent, and K2O application rate over 300 kg/hm2 orchards was 15.9 percent while no 22.7 percent orchards without any K applied. The investigation demonstrated that 25.5 and 63.6 percent orchards applied fertilizer once and twice in whole year which reflected mulberry fertilization times was too few.