Welcome to Chinese Agricultural Science Bulletin,

Chinese Agricultural Science Bulletin ›› 2005, Vol. 21 ›› Issue (7): 7-7.

Special Issue: 生物技术

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Effects of Secondary Metabolites of Rhizoctonia Leguminicola on Hepatoma 22 cells were observed by TEM

Zhang Li, Yang Mingqi   

  • Online:2005-07-05 Published:2005-07-05

Abstract: During the study, we built cancer mold by transplanting Hepatoma 22 cells to rats, and pour the secondary metabolites of Rhizoctonia Leguminicola which have swainsonine into the stomach of the rats, and the doses of swainsonine are 2.7 mg·kg-1·d-1 and 16.2 mg·kg-1·d-1 separately. The pathology changes were observed by TEM. The result shows that the secondary metabolites can inhibit tumor growth and metastasis. Above all, the secondary metabolites of Rhizoctonia Leguminicola have similar function with swainsonine. And they have value as antitumor drugs.