Abstract:

Compound vitamin liposomes were prepared by freeze-drying-comminuting-sieving. Soybean phospholipid powder was selected as coating material. The mixture of thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid and nicotinamide was used as core material. Influences of ratio of coating material to core material on the loading and encapsulation efficiency of vitamins in liposomes were investigated. Results indicated that as the ratio of coating material to core material increased, the encapsulation efficiency of vitamins increased while the loading of vitamins decreased. The optimum ratio of coating material to core material was 15 / 1(w / w).