Abstract:

In order to detect peripheral blood of BALB/c mice infected with Mycoplasma suis were affected, To investigate the changes of CD35, CD58 and CD59 in peripheral blood of BALB/c mice with the Mycoplasma suis with the method of ELISA on the 1, 3, 5, 7, 9 days. The results showed that CD35 of erythrocyte surface gradually decline and on the 1, 3, 5, 7, 9 days, CD35, CD58 and CD59 in the plasma of mice infected with Mycoplasma suis was respectively significantly higher than the control group(P＜0.01). On the third day, CD35, CD58 and CD59 concentration in the plasma of mice raised to the highest point(P＜0.01). Results demonstrated that the lever of CD35, CD58 and CD59 in peripheral blood of BALB/c mice infected with Mycoplasma suis were increased, and raised to the highest point on the third day. The CD35, CD58 and CD59 in the erythrocyte surface were damaged after mice infected Mycoplasma suis, the immunity of erythrocytes were further affected.