Abstract: The leaves tissue structure of flue-cured tobacco ‘KRK26’ were studied by microscopic observation with there curing techniques “Zimbabwe cured”, “three phase drying cured” and “quality and aroma cured”. The result showed that: (1) With the three kinds of curing techniques, the leaf thickness, palisade tissue, spongy tissue of the flue-cured tobacco were gradually shrink, and there were small changes in the thickness of the upper and lower epidermis, because of different curing techniques, the tissue structure shrinkage peak performance showed different characteristics: a contraction peak of leave thickness. (2) Under the different curing techniques, and with the curing time lengthening that stoma ports of all samples had the obvious deformation, and the changes from closed to opened and then closed again of the stomas of lower epiderm of the central leaves of flue-cured tobacco were observed. (3) “Quality and aroma cured” technique, at the cured 84 h, the integrity of leaves tissue structural was better than the other two cured techniques. Dry ball temperature was (42±1)℃, wet ball temperature was (36±1)℃, maintained dry wet ball temperature difference was 6-8℃.