Abstract: This study aimed at determining the response to Chinese stripe rust races, the origin and inheritance mode of resistance gene in a new Thinopyrum ponticum-derived wheat introgression line CH7102. Seedlings of Th. ponticum (accession R431), CH7102 and its resistant parent partial amphiploid‘Xiaoyan 7430’as well as all wheat parents were evaluated in the greenhouse using CYR31 and CYR32, the most widely virulent and predominant pathotypes in China. CH7102 was crossed respectively to susceptible cultivars‘Taichung 29’and‘Mianyang 11’and the lines containing known resistance genes, and the resulting segregating populations F2, F3 and BC1 were used for genetic analysis of stripe rust response and allelism tests of resistance gene in CH7102. When inoculated with race CYR32 at the adult plant stage, F1 plants from both crosses showed infection types (IT) similar to the resistant parent, indicating that resistance was dominant. The segregation ratios in the F2 and BC1 populations and F3 lines were consistent with those expected for segregation at a single locus. When tested with the same race at the seedling stage, the segregation for resistant and susceptible showed a good fit with a 15:1 ratio in all F2 populations from crossing CH7102 with five lines containing known resistance genes. The stripe rust resistance in wheat-alien introgression line CH7102 was controlled by a single dominant gene, presumably having been transferred from T. ponticum. Based on the result from allelism tests, the resistance gene in CH7102 was different from the known effective resistance genes Yr5, Yr10, Yr15 Yr24/ Yr26 and Yr41, and is possibly a new gene for resistance to stripe rust.