Abstract:

The ginseng protein was extracted from ginseng powder, and the inhibitory activity of angiotensin I-converting enzyme (ACE) was detected. Ginseng powder was prepared by stirring in water (pH 9.0), followed by centrifugation at 3000 r/m for 20 min. An ACE inhibitor was purified by using consecutive chromatographic methods, including: D101 macroporous resin chromatography, ion-exchange chromatography, and gel filtration chromatography. The inhibitory activity of ACE was determined as ACE inhibitory activity in vitro of ginseng protein. The ginseng protein had inhibitory activity for ACE, the ACE inhibitor could be extracted by using consecutive chromatographic methods, and the ACE inhibitory ratio could achieve 92.5%.