Abstract:

The aim was to study the antiviral effects between Flos Lonicerae japonicae and Flos lonicerae which were very different in price. Chlorogenic acids were extracted from them. The antiviral effects of the Chlorogenic acids extracts on the infection of Newcastle disease virus (NDV) to cells were investigated by observing cytopathic effect (CPE) in Vero cell, and the cell survival rate by MTT method was detected. The antivirus effects of Flos Lonicerae japonicae and Flos Lonicerae were compareed. The results showed that the chlorogenic acids ingredients from Flos Lonicerae japonicae and Flos Lonicerae had significant antivirus function in safe concentration; the chlorogenic acids extracts had obvious interdiction, inhibition and neutralization effects to NDV in Vero cell. There were no obvious differences between Flos Lonicerae japonicae and Flos Lonicerae in the antivirus effects. It will give the test proof that the cheaper Flos Lonicerae can take part place of Lonicera japonica japonicae in a certain area.