Abstract:

To further develop and utilize T4 phage display and phage therapy, and open the broader prospect for the progress in study of T4 phage, the important components of T4 phage particles was analyzed by molecular biology techniques, such as the head, the tail and the basement. The protein composition of these structure were confirmed. DNA packing which was an important part in the assembly of T4 phage particle was described in detail. Not only the phenomenon of infection and lysis, but also the superinfection exclusion and lysis inhibition in T4 life cycles was introduced with molecular mechanism and impact factor. The assembly and infection mechanism of T4 phage would be known much better by these research.