Abstract:

To study the scavenging effect of hydroxyl radical and DPPH? and antioxidant capacity of small collagen peptide (CPI). DPPH? and hydroxyl radical scavenging system was adopted to evaluate the scavenging effect; The activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and content of malondialdehyde (MDA) in blood serum and liver tissue in D-galactose treated mice were analyzed. The results showed that the scavenging ability of DPPH? radical was 80% in 10 mg/mL level and the scavenging ability of hydroxyl radical was 91.56% in 40 mg/mL level. Malondi-aldehyde (MDA)content revealed a significant decrease in serum and liver (P＜0.01) and Super Oxidase Dimutase (SOD) and Glutathione Per-oxidase (GSH-Px) activity revealed a significant increase (P＜0.05) than model group. Small collagen peptide (＜1000Da) has obvious antioxidant activity.