Abstract:

In order to investigate antimicrobial effect to chicken E.coli on Chinese herbal preparation of Yinqiaotiangan in vivo, The prevention and treatment test was carried with 15 days age chicken. In the prevention trial these chicken were attacked by the O2 type E.coli and taken orally 0.5mL,1.0mL and 2.0mL Chinese herbal preparation of Yinqiaotiangan respectively, at the same time. And then the incidence, mortality, and protective rate were detected when the Chinese herbal preparation were continuous used 10 d, once a day. In the treatment test these chicken were attacked by the O2 type E.coli and established the O2 type E.coli disease model, following taken orally 0.5mL,1.0mL and 2.0mL Chinese herbal preparation of Yinqiaotiangan respectively and injected cephalosporin latter sodium as positive control. The cure rate, effective rate and incidence were detected when the Chinese herbal preparation were continuous used 10 d, twice a day. The prevention trial results showed that the protective rate in experimental groups were higher than those in control (P<0.05),the incidence and mortality were lower than that of the control at 18th day (P<0.01),and the protective rate of middle and high dose group reached above 85%.The treatment test results showed that the incidence of the Chinese herbal preparation groups was lower than that of cephalosporin latter sodium group(P<0.05), the cure rate of middle and high dose group were higher than that of cephalosporin latter sodium group(P<0.05 or P<0.01) , and the effective rate of high dose group was higher than that of cephalosporin latter sodium group(P<0.01).So chicken E.coli disease could be effectively prevented and treated by oral the preparation of Yinqiaotiangan.