Abstract: A2–CMS of sorghum was invented by Mr. Schertz who was an American sorghum breeder in 1976. It was imported into China in1979. Its cytoplasm came from Ethiopia and its nucleus from India. A pair of nucleus gene and cytoplasm gene take common effects on A2–CMS. Its genotype is S2 (ms2 ms2 ), and B line is F2 (ms2 ms2 ) and R line is F2 or S2 (Ms2 Ms2 ). If the line can recover or maintain A1–CMS. The same effect to A2–CMS too. A little R line appear maintainer type. So, it has wider maintainer resources. The temperature is main factor to fertility. Under the natural condition, the pistil of A2–CMS has little abortion or no abortion and the stamen can shed pollen with high temperature which make a little self-seed. The heterosis and combining ability of the main agronomic characters have no significant difference between A2–CMS and A1–CMS. The first A2–CMS-V4A was bred by Academy of Agricultural sciences of Shanxi Province in 1987 in the world and the first hybrid-Jinza 12 which gained Sci-technology Progress Second Class Award in 1997 was compounded too. 5 hybrid have been approved by the Provincial Class Committee of Crop Variety Identification. Therefore, the A2–CMS gained National Invention Third Class Award in 1998. Siza 25 was bred with A2TAM428χNAN133 by original Siping Academy of Agricultural Sciences of Jilin Province with A2–CMS and it gained Sci-technology Progress Second Class Award of Jilin Province in 2002. Jiza No.80, 83, 96, 97 were bred with A2–CMS in Academy of Agricultural Sciences of Jilin Province. Liaoza 10 was bred in Academy of Agricultural Sciences of Liaoning Province. These hybrids are popularized widely now with large areas. The abortion of reaction and application of Non-Milo-CMS were discussed in this paper.