Abstract: Liuyangmycin, dynamic material against mites, are isolated from fermentation of Streptomyces griseius var. liuyangensis. Control tests of 10% EC Liuyangmycin against Acaphylla theae (Watt) were done in laboratory, field plot and field respectively. In laboratory tests, when applied at 1:1000 solution on A. theae, 10% EC Liuyangmycin provided 95.3% insect control 10 after application, which compared with 89.3% mortality for application 1:1, 500 solution. Control effect of 10% EC Liuyangmycin 1:1,000 solution and 1:1,500 solution against A. theae reached 86.9% and 85.6% respectively, 10 days after the application in the field plot experiment. Application of the miticide (1:1,200 solution) against A. theae showed that the integrated control effect obtain 86.1% (5 days) and even 57.9% (30 days) in the field trial. In field tests 10% EC Liuyangmycin 1:1,000 solution provided 80.6%, 71.2%, 43.8% average efficacy after 5d, 15d, 30d. Those control effects were as good as the treatments of Avermecinbla and Phoxim. It is a kind of safety biological pesticide with high efficient, low toxic and low residue peculiarity, which applied in tea gardens.