Abstract: Huanglongbing is a cosmopolitan and destructive disease, besides its distribution in Asia and Africa，now the disease and its vector –citrus psylla have been found in Brazil and America as well. Due to citrus psylla is the only vector of huanglongbing and disease-free seedlings cannot be cultured in isolation, huanglongbing has become the biggest obstacle in the development of citrus industry in Guangxi. A new theory of integrated control of huanglongbing has been proposed and applied for three years in the largest citrus planting area. The new theory described that huanglongbing is the most destructive disease and citrus psylla is the most destructive pest. Integrated control citrus psylla is the most effective means in the integrated control system of huanglongbing in the diseased area. The new theory is applied in the test area for three years, the total incidence of huanglongbing in the test area was 0.74% , less 8.68% than the total incidence (9.42%)in the contrastⅠ, less 6.40% than the total incidence(7.14%) in the contrastⅡ.