Abstract: Six medicine plants crude extracts were used to test the insectici activities against the larvae of Yponomeutidae evonymellus L. in laboratory. The results showed that the insectici activities of the extracts from roof of Phytolacca acinosa Roxb. is higher than other plants’. The stomach toxicity of Phytolacca acinosa Roxb. against the larvae of Yponomeutidae evonymellus L. reached 72.73% within 72h, and the growth inhibition rate was 72.08%. The result also showd that the extract of Yponomeutidae evonymellus L also have some contact toxicity agaist the larvae . All results indicated that Yponomeutidae evonymellus L is worth to study and exploit.