Abstract: The performance of sci-tech extension, an important part of the agriculture integrated development project,directly affects the progress of the project.With analysis, this paper reached that the Sci-tech extension for agriculture integrated development has the basic characteristics of comprehension,dominance,popularity and application.According to the concrete practice of Nantong and with mechanism innovation as the breakthrough point, new work mode was explored from the aspects of operation,organization, extension of the Sci-tech extension for agriculture integrated development.Innovating operation mode through trust-and-clientage method, creating new organization mode by establishing extension project team and blazing new trails in extension mode by mechanism were put forward. The Sci-tech extension was significantly effectively and played a supporting role in the project of agriculture integrated development in Nantong high-quality rice industry park which was given as an example.