Abstract: Pseudomonas solanacearum, Phytophthora nicotianae and thielariopsis basicola are primary diseases at southward of China. At present, Composition prevention and cured was used mainly, cropping resist breed, chymic and biologic prevention ande cured were included. But they have localization, could not cure radically. “Filled singleness medicine into stalk”, “Tom-time interose an two-time fill” and “Filled three medicines into stalk” were used throuth 2004—2006.The resoult showed that: “Tom-time interose an two-time fill” and “Filled three medicines into stalk” were obviously.