Abstract: The probe and primers were designed and synthesized according to the growth hormone receptor sequence of goose available in GenBank. Then a real-time RT-PCR assay was developed and assessed. Results showed that the standard curve made by pMD-18T-GHR had good linear dependence, and the fluorescent quantitative RT-PCR assay was sensitive, specific and reliable. The expression of GHR mRNA were difference in liver during postnatal 90 days , and there was different changing pattern in other tissues at 30 days between Zigeese and Rhine.