Abstract: Field experiments were conducted to research the effects of bio-fertilizer on saline soil bulk density, microorganism amounts, soil saline distribution and Chinese cabbage quality. The results indicated that compared to no fertilizer, fertilizer treatments and base treatment, respectively, mixed microorganism fertilizer could increase soil bacteria amount 106.04%, 58.99% and 48.12%, while decreased soil bulk density 0.05g/cm3, 0.03g/cm3 and 0.02g/cm3. Mixed microorganism fertilizer could effectively decrease soil salinity in plowing depth, but had little decreased effect on 1 m soil depth. Applying mixed microorganism fertilizer could improved Chinese cabbage quality, which decreased plant Nitrate content by 0.14mg/kg and 1.80mg/kg, while increased soluteable sugar content by 0.4% and 0.8% compared to no fertilizer and fertilizer treatments, respectively.