Abstract: 【Objective】In order to overcome drug resistance of the ESBLs producing bactera ，to instruct the veterinary drug,use in clinic。【Method】 Five Enterobacteriaceaes isolated from swine and chicken , tested for ESBL by double –disk methord, were studied ESBLs gene type with amplified by PCR .【Result】the ESBLs producing bactera amplified by PCR with TEM-type down-object while SHV-type down –object did not.【Conclusion】ESBLs producing Enterobacteriaceaes from swine and avian have not exchanged resistant gene through plasmid in china.