Abstract: Abstract: By using the method of boiling-water extraction、ethanol extraction and orthogonal, the water-soluble and extracts ethanol-soluble extracts were obtained from Indocalamus leaves, and the results showed that when the water-soluble extraction condition was at the ratio of material 15g to liquid 200ml, extracting temperature 110℃ and extracting time 120min, the absorbance tested was highest. The ethanol-soluble extraction condition was extracting time 90min , extracting temperature 110℃,and quality score 90%, and the absorbance tested was highest. In the experiment of scavenging activity to O2-,the concentration of water-soluble extracts between 0.4～51.2mg/ml showed growing tendency, when the concentration was 51.2mg/ml,the scavenging rate was 33.33%. The ethanol-soluble extracts showed negative growing tendency. In the experiment of scavenging activity to •OH, the concentration of water-soluble extracts between 0.4～51.2mg/ml showed growing tendency, when the concentration was 51.2mg/ml,the scavenging rate was 13.88%. The ethanol-soluble extracts showed negative growing tendency. When the concentration exceed 6.4mg/ml, negative growing tendency was significant, even reached -93.75%. In conclusion, the water-soluble extracts of Indocalamus leaves had relatively strong antioxidant activity, so its application value is wide.